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Examining the freezing process of an intermediate bulk containing an industrially relevant protein
Numerous biopharmaceuticals are produced in recombinant microorganisms in the controlled environment of a bioreactor, a process known as Upstream Process. To minimize product loss due to physico-chemical and enzymatic degradation, the Upstream Process should be directly followed by product purificat...
Autores principales: | Reinsch, Holger, Spadiut, Oliver, Heidingsfelder, Johannes, Herwig, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370381/ https://www.ncbi.nlm.nih.gov/pubmed/25765305 http://dx.doi.org/10.1016/j.enzmictec.2015.01.003 |
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