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Potentiation of Insulin-Mediated Glucose Lowering without Elevated Hypoglycemia Risk by a Small Molecule Insulin Receptor Modulator

Insulin resistance is the key feature of type 2 diabetes and is manifested as attenuated insulin receptor (IR) signaling in response to same levels of insulin binding. Several small molecule IR activators have been identified and reported to exhibit insulin sensitization properties. One of these mol...

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Detalles Bibliográficos
Autores principales: Wu, Margaret, Dai, Ge, Yao, Jun, Hoyt, Scott, Wang, Liangsu, Mu, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370409/
https://www.ncbi.nlm.nih.gov/pubmed/25799496
http://dx.doi.org/10.1371/journal.pone.0122012