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CXCR3 Signaling in BRAF(WT) Melanoma Increases IL-8 Expression and Tumorigenicity

Patients with early stage, radial growth phase (RGP) melanoma have a 97% survival rate; however, when the melanoma progresses to the invasive vertical growth phase (VGP), survival rates decrease to 15%. The targets of many clinical trials are the known genetic and molecular mechanisms involved in me...

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Detalles Bibliográficos
Autores principales: Jenkins, Molly H., Brinckerhoff, Constance E., Mullins, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370421/
https://www.ncbi.nlm.nih.gov/pubmed/25798946
http://dx.doi.org/10.1371/journal.pone.0121140