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Persistence of Transmitted HIV-1 Drug Resistance Mutations Associated with Fitness Costs and Viral Genetic Backgrounds

Transmission of drug-resistant pathogens presents an almost-universal challenge for fighting infectious diseases. Transmitted drug resistance mutations (TDRM) can persist in the absence of drugs for considerable time. It is generally believed that differential TDRM-persistence is caused, at least pa...

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Detalles Bibliográficos
Autores principales: Yang, Wan-Lin, Kouyos, Roger D., Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Aubert, Vincent, Scherrer, Alexandra U., Shilaih, Mohaned, Hinkley, Trevor, Petropoulos, Christos, Bonhoeffer, Sebastian, Günthard, Huldrych F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370492/
https://www.ncbi.nlm.nih.gov/pubmed/25798934
http://dx.doi.org/10.1371/journal.ppat.1004722