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Persistence of Transmitted HIV-1 Drug Resistance Mutations Associated with Fitness Costs and Viral Genetic Backgrounds
Transmission of drug-resistant pathogens presents an almost-universal challenge for fighting infectious diseases. Transmitted drug resistance mutations (TDRM) can persist in the absence of drugs for considerable time. It is generally believed that differential TDRM-persistence is caused, at least pa...
Autores principales: | Yang, Wan-Lin, Kouyos, Roger D., Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Aubert, Vincent, Scherrer, Alexandra U., Shilaih, Mohaned, Hinkley, Trevor, Petropoulos, Christos, Bonhoeffer, Sebastian, Günthard, Huldrych F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370492/ https://www.ncbi.nlm.nih.gov/pubmed/25798934 http://dx.doi.org/10.1371/journal.ppat.1004722 |
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