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High Salt Intake Damages the Heart through Activation of Cardiac (Pro) Renin Receptors Even at an Early Stage of Hypertension

OBJECTIVE: It has not yet been fully elucidated whether cardiac tissue levels of prorenin, renin and (P)RR are activated in hypertension with a high salt intake. We hypothesized that a high salt intake activates the cardiac tissue renin angiotensin system and prorenin-(pro)renin receptor system, and...

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Detalles Bibliográficos
Autores principales: Hayakawa, Yuka, Aoyama, Takuma, Yokoyama, Chiharu, Okamoto, Chihiro, Komaki, Hisaaki, Minatoguchi, Shingo, Iwasa, Masamitsu, Yamada, Yoshihisa, Kawamura, Itta, Kawasaki, Masanori, Nishigaki, Kazuhiko, Mikami, Atsushi, Suzuki, Fumiaki, Minatoguchi, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370564/
https://www.ncbi.nlm.nih.gov/pubmed/25799069
http://dx.doi.org/10.1371/journal.pone.0120453