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High Salt Intake Damages the Heart through Activation of Cardiac (Pro) Renin Receptors Even at an Early Stage of Hypertension
OBJECTIVE: It has not yet been fully elucidated whether cardiac tissue levels of prorenin, renin and (P)RR are activated in hypertension with a high salt intake. We hypothesized that a high salt intake activates the cardiac tissue renin angiotensin system and prorenin-(pro)renin receptor system, and...
Autores principales: | Hayakawa, Yuka, Aoyama, Takuma, Yokoyama, Chiharu, Okamoto, Chihiro, Komaki, Hisaaki, Minatoguchi, Shingo, Iwasa, Masamitsu, Yamada, Yoshihisa, Kawamura, Itta, Kawasaki, Masanori, Nishigaki, Kazuhiko, Mikami, Atsushi, Suzuki, Fumiaki, Minatoguchi, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370564/ https://www.ncbi.nlm.nih.gov/pubmed/25799069 http://dx.doi.org/10.1371/journal.pone.0120453 |
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