Cargando…

p38 MAP Kinase Inhibitor Suppresses Transforming Growth Factor-β2–Induced Type 1 Collagen Production in Trabecular Meshwork Cells

Glaucoma is an age-related neurodegenerative disease of retinal ganglion cells, and appropriate turnover of the extracellular matrix in the trabecular meshwork is important in its pathology. Here, we report the effects of Rho-associated kinase (ROCK) and p38 MAP kinase on transforming growth factor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Inoue-Mochita, Miyuki, Inoue, Toshihiro, Fujimoto, Tomokazu, Kameda, Takanori, Awai-Kasaoka, Nanako, Ohtsu, Naoki, Kimoto, Kenichi, Tanihara, Hidenobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370581/ https://www.ncbi.nlm.nih.gov/pubmed/25799097 http://dx.doi.org/10.1371/journal.pone.0120774

Ejemplares similares

Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability
por: Awai-Kasaoka, Nanako, et al.
Publicado: (2013)

Inhibition of Rho Kinase Induces Antioxidative Molecules and Suppresses Reactive Oxidative Species in Trabecular Meshwork Cells
por: Fujimoto, Tomokazu, et al.
Publicado: (2017)

Vascular Endothelial Growth Factor-A Increases the Aqueous Humor Outflow Facility
por: Fujimoto, Tomokazu, et al.
Publicado: (2016)

Suberoylanilide hydroxamic acid (SAHA) inhibits transforming growth factor-beta 2-induced increases in aqueous humor outflow resistance
por: Fujimoto, Tomokazu, et al.
Publicado: (2021)

DNA methyltransferase inhibitor suppresses fibrogenetic changes in human conjunctival fibroblasts
por: Yonemura, Hitomi, et al.
Publicado: (2019)

Fornix-based versus limbal-based conjunctival flaps in trabeculectomy with mitomycin C in high-risk patients
por: Kuroda, Utako, et al.
Publicado: (2014)

Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells
por: Kaneko, Yoshio, et al.
Publicado: (2016)

The effects of exosomes derived from trabecular meshwork cells on Schlemm’s canal endothelial cells
por: Takahashi, Eri, et al.
Publicado: (2021)

TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness
por: Matsumura, Tomoyo, et al.
Publicado: (2020)

A ROCK inhibitor suppresses the transforming growth factor-beta-2-induced endothelial–mesenchymal transition in Schlemm’s canal endothelial cells
por: Fujimoto, Tomokazu, et al.
Publicado: (2023)

Correction: TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness
por: Matsumura, Tomoyo, et al.
Publicado: (2021)

Three-dimensional architecture of collagen type VI in the human trabecular meshwork
por: Koudouna, Elena, et al.
Publicado: (2014)

Rho-associated protein kinase inhibitor induced morphological changes in type VI collagen in the human trabecular meshwork
por: Okamoto, Mizu, et al.
Publicado: (2020)

Human Trabecular Meshwork Progenitors
por: Zhu, Qin, et al.
Publicado: (2019)

YAP and TAZ mediate steroid-induced alterations in the trabecular meshwork cytoskeleton in human trabecular meshwork cells
por: Peng, Jie, et al.
Publicado: (2018)

Apoptosis in the trabecular meshwork of glaucomatous patients
por: Baleriola, Jimena, et al.
Publicado: (2008)

Two-photon imaging of the trabecular meshwork
por: Ammar, David A., et al.
Publicado: (2010)

Surgery on the Trabecular Meshwork: Histopathological Evidence
por: Bhartiya, Shibal, et al.
Publicado: (2015)

Oxidative stress and antioxidants in the trabecular meshwork
por: Wang, Mingxuan, et al.
Publicado: (2019)

Comparative Study of the Effects of Trabecular Meshwork Outflow Drugs on the Permeability and Nitric Oxide Production in Trabecular Meshwork Cells
por: Kim, Jae Woo
Publicado: (2017)

Prediction of trabecular meshwork-targeted micro-invasive glaucoma surgery outcomes using anterior segment OCT angiography
por: Okamoto, Yoko, et al.
Publicado: (2021)

Age-Related Changes in Trabecular Meshwork Imaging
por: Gold, Mark E., et al.
Publicado: (2013)

An In-Depth View of the Porcine Trabecular Meshwork Proteome
por: Funke, Sebastian, et al.
Publicado: (2019)

Sampling trabecular meshwork using TrabEx+
por: Ramjiani, Vipul, et al.
Publicado: (2021)

Primary Human Trabecular Meshwork Model for Pseudoexfoliation
por: Chakraborty, Munmun, et al.
Publicado: (2021)

An Optimized Method to Decellularize Human Trabecular Meshwork
por: Crouch, Devon J., et al.
Publicado: (2022)

Endoplasmic Reticulum Stress Response of Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells and Protective Effects of Activated PERK Pathway
por: Wang, Yiwen, et al.
Publicado: (2019)

Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes
por: Fujimoto, Tomokazu, et al.
Publicado: (2021)

Trabecular meshwork's collagen network formation is inhibited by non‐pigmented ciliary epithelium‐derived extracellular vesicles
por: Tabak, Saray, et al.
Publicado: (2021)

Changes in the deep vasculature assessed using anterior segment OCT angiography following trabecular meshwork targeted minimally invasive glaucoma surgery
por: Okamoto, Yoko, et al.
Publicado: (2022)

ETX1 is over-expressed in the glaucomatous trabecular meshwork
por: Iragavarapu, Saradha, et al.
Publicado: (2009)

Wnt gene expression in human trabecular meshwork cells
por: Shyam, Rajalekshmy, et al.
Publicado: (2010)

A20 Attenuates the Fibrotic Response in the Trabecular Meshwork
por: Mzyk, Philip, et al.
Publicado: (2022)

Toll-Like Receptor 4 Signaling in the Trabecular Meshwork
por: Mzyk, Philip, et al.
Publicado: (2022)

Segmental outflow dynamics in the trabecular meshwork of living mice
por: Reina-Torres, Ester, et al.
Publicado: (2022)

Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography
por: Kojima, Sachi, et al.
Publicado: (2014)

Angle closure caused by a plateau-like iris associated with an enlarged Soemmering’s ring: a case report
por: Kitamura, Fumika, et al.
Publicado: (2016)

Data on early postoperative changes in aqueous monocyte chemoattractant protein-1 levels after phacoemulsification
por: Kawai, Motofumi, et al.
Publicado: (2016)

Trabecular Meshwork Gene Expression after Selective Laser Trabeculoplasty
por: Izzotti, Alberto, et al.
Publicado: (2011)

Decreased carbohydrate metabolism enzyme activities in the glaucomatous trabecular meshwork
por: Junk, Anna K., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_88n14k3bqig1kb8d74c5vmrlf7