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Design and Characterization of a Membrane Protein Unfolding Platform in Lipid Bilayers
Accurate measurement of membrane protein stability—and particularly how it may vary as a result of disease-phenotypic mutations—ideally requires a denaturant that can unfold a membrane-embedded structure while leaving the solubilizing environment unaffected. The steric trap method fulfills this requ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370600/ https://www.ncbi.nlm.nih.gov/pubmed/25799099 http://dx.doi.org/10.1371/journal.pone.0120253 |