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Detection of G-Quadruplex DNA Using Primer Extension as a Tool

DNA sequence and structure play a key role in imparting fragility to different regions of the genome. Recent studies have shown that non-B DNA structures play a key role in causing genomic instability, apart from their physiological roles at telomeres and promoters. Structures such as G-quadruplexes...

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Detalles Bibliográficos
Autores principales: Kumari, Rupa, Nambiar, Mridula, Shanbagh, Shaika, Raghavan, Sathees C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370603/
https://www.ncbi.nlm.nih.gov/pubmed/25799152
http://dx.doi.org/10.1371/journal.pone.0119722