Behavioral and Electrophysiological Characterization of Dyt1 Heterozygous Knockout Mice

DYT1 dystonia is an inherited movement disorder caused by mutations in DYT1 (TOR1A), which codes for torsinA. Most of the patients have a trinucleotide deletion (ΔGAG) corresponding to a glutamic acid in the C-terminal region (torsinA(ΔE)). Dyt1 ΔGAG heterozygous knock-in (KI) mice, which mimic ΔGAG...

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Detalles Bibliográficos
Autores principales: Yokoi, Fumiaki, Chen, Huan-Xin, Dang, Mai Tu, Cheetham, Chad C., Campbell, Susan L., Roper, Steven N., Sweatt, J. David, Li, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370625/
https://www.ncbi.nlm.nih.gov/pubmed/25799505
http://dx.doi.org/10.1371/journal.pone.0120916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370625/
https://www.ncbi.nlm.nih.gov/pubmed/25799505
http://dx.doi.org/10.1371/journal.pone.0120916

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