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Fibrillar Amyloid Plaque Formation Precedes Microglial Activation

In Alzheimer’s disease (AD), hallmark β-amyloid deposits are characterized by the presence of activated microglia around them. Despite an extensive characterization of the relation of amyloid plaques with microglia, little is known about the initiation of this interaction. In this study, the detaile...

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Detalles Bibliográficos
Autores principales: Jung, Christian K. E., Keppler, Kevin, Steinbach, Sonja, Blazquez-Llorca, Lidia, Herms, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370641/
https://www.ncbi.nlm.nih.gov/pubmed/25799372
http://dx.doi.org/10.1371/journal.pone.0119768