Functional Characterization of the 1,5-Benzodiazepine Clobazam and Its Major Active Metabolite N-Desmethylclobazam at Human GABA(A) Receptors Expressed in Xenopus laevis Oocytes

The 1,5-benzodiazepine clobazam is indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in patients 2 years of age or older in the United States, and for treatment of anxiety and various forms of epilepsy elsewhere. Clobazam has been reported to exhibit differen...

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Detalles Bibliográficos
Autores principales: Hammer, Harriet, Ebert, Bjarke, Jensen, Henrik Sindal, Jensen, Anders A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370687/
https://www.ncbi.nlm.nih.gov/pubmed/25798598
http://dx.doi.org/10.1371/journal.pone.0120239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370687/
https://www.ncbi.nlm.nih.gov/pubmed/25798598
http://dx.doi.org/10.1371/journal.pone.0120239

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