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Functional Characterization of the 1,5-Benzodiazepine Clobazam and Its Major Active Metabolite N-Desmethylclobazam at Human GABA(A) Receptors Expressed in Xenopus laevis Oocytes

The 1,5-benzodiazepine clobazam is indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in patients 2 years of age or older in the United States, and for treatment of anxiety and various forms of epilepsy elsewhere. Clobazam has been reported to exhibit differen...

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Detalles Bibliográficos
Autores principales:	Hammer, Harriet, Ebert, Bjarke, Jensen, Henrik Sindal, Jensen, Anders A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370687/ https://www.ncbi.nlm.nih.gov/pubmed/25798598 http://dx.doi.org/10.1371/journal.pone.0120239

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