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Activation of CNTF/CNTFRα Signaling Pathway by hRheb(S16H) Transduction of Dopaminergic Neurons In Vivo

Ciliary neurotrophic factor (CNTF) is one of representative neurotrophic factors for the survival of dopaminergic neurons. Its effects are primarily mediated via CNTF receptor α (CNTFRα). It is still unclear whether the levels of CNTFRα change in the substantia nigra of Parkinson’s disease (PD) pati...

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Detalles Bibliográficos
Autores principales: Jeong, Kyoung Hoon, Nam, Jin Han, Jin, Byung Kwan, Kim, Sang Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370699/
https://www.ncbi.nlm.nih.gov/pubmed/25799580
http://dx.doi.org/10.1371/journal.pone.0121803