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K(+)-Dependent Selectivity and External Ca(2+) Block of Shab K(+) Channels

Potassium channels allow the selective flux of K(+) excluding the smaller, and more abundant in the extracellular solution, Na(+) ions. Here we show that Shab is a typical K(+) channel that excludes Na(+) under bi-ionic, Na(o)/K(i) or Na(o)/Rb(i), conditions. However, when internal K(+) is replaced...

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Detalles Bibliográficos
Autores principales: Carrillo, Elisa, Pacheco, Lucero, Balleza, Daniel, Gomez-Lagunas, Froylan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370708/
https://www.ncbi.nlm.nih.gov/pubmed/25798591
http://dx.doi.org/10.1371/journal.pone.0120431