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Co-Conserved MAPK Features Couple D-Domain Docking Groove to Distal Allosteric Sites via the C-Terminal Flanking Tail

Mitogen activated protein kinases (MAPKs) form a closely related family of kinases that control critical pathways associated with cell growth and survival. Although MAPKs have been extensively characterized at the biochemical, cellular, and structural level, an integrated evolutionary understanding...

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Detalles Bibliográficos
Autores principales: Nguyen, Tuan, Ruan, Zheng, Oruganty, Krishnadev, Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370755/
https://www.ncbi.nlm.nih.gov/pubmed/25799139
http://dx.doi.org/10.1371/journal.pone.0119636