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Co-Conserved MAPK Features Couple D-Domain Docking Groove to Distal Allosteric Sites via the C-Terminal Flanking Tail
Mitogen activated protein kinases (MAPKs) form a closely related family of kinases that control critical pathways associated with cell growth and survival. Although MAPKs have been extensively characterized at the biochemical, cellular, and structural level, an integrated evolutionary understanding...
Autores principales: | Nguyen, Tuan, Ruan, Zheng, Oruganty, Krishnadev, Kannan, Natarajan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370755/ https://www.ncbi.nlm.nih.gov/pubmed/25799139 http://dx.doi.org/10.1371/journal.pone.0119636 |
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