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VDJSeq-Solver: In Silico V(D)J Recombination Detection Tool

In this paper we present VDJSeq-Solver, a methodology and tool to identify clonal lymphocyte populations from paired-end RNA Sequencing reads derived from the sequencing of mRNA neoplastic cells. The tool detects the main clone that characterises the tissue of interest by recognizing the most abunda...

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Detalles Bibliográficos
Autores principales: Paciello, Giulia, Acquaviva, Andrea, Pighi, Chiara, Ferrarini, Alberto, Macii, Enrico, Zamo’, Alberto, Ficarra, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370828/
https://www.ncbi.nlm.nih.gov/pubmed/25799103
http://dx.doi.org/10.1371/journal.pone.0118192