Targeted delivery of polyamidoamine-paclitaxel conjugate functionalized with anti-human epidermal growth factor receptor 2 trastuzumab

BACKGROUND: Antibody-dendrimer conjugates have the potential to improve the targeting and release of chemotherapeutic drugs at the tumor site while reducing adverse side effects caused by drug accumulation in healthy tissues. In this study, trastuzumab (TMAB), which binds to human epidermal growth f...

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Detalles Bibliográficos
Autores principales: Ma, Pengkai, Zhang, Xuemei, Ni, Ling, Li, Jinming, Zhang, Fengpu, Wang, Zheng, Lian, Shengnan, Sun, Kaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370923/
https://www.ncbi.nlm.nih.gov/pubmed/25834432
http://dx.doi.org/10.2147/IJN.S77152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370923/
https://www.ncbi.nlm.nih.gov/pubmed/25834432
http://dx.doi.org/10.2147/IJN.S77152

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