Caught in Action: Selecting Peptide Aptamers Against Intrinsically Disordered Proteins in Live Cells

Intrinsically disordered proteins (IDPs) or unstructured segments within proteins play an important role in cellular physiology and pathology. Low cellular concentration, multiple binding partners, frequent post-translational modifications and the presence of multiple conformations make it difficult...

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Detalles Bibliográficos
Autores principales: Cobbert, Jacqueline D., DeMott, Christopher, Majumder, Subhabrata, Smith, Eric A., Reverdatto, Sergey, Burz, David S., McDonough, Kathleen A., Shekhtman, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371151/
https://www.ncbi.nlm.nih.gov/pubmed/25801767
http://dx.doi.org/10.1038/srep09402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371151/
https://www.ncbi.nlm.nih.gov/pubmed/25801767
http://dx.doi.org/10.1038/srep09402

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