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Caught in Action: Selecting Peptide Aptamers Against Intrinsically Disordered Proteins in Live Cells
Intrinsically disordered proteins (IDPs) or unstructured segments within proteins play an important role in cellular physiology and pathology. Low cellular concentration, multiple binding partners, frequent post-translational modifications and the presence of multiple conformations make it difficult...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371151/ https://www.ncbi.nlm.nih.gov/pubmed/25801767 http://dx.doi.org/10.1038/srep09402 |