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Mechanistic insights into pancreatic beta-cell mass regulation by glucose and free fatty acids
Pancreatic islets are responsible for blood glucose homeostasis. Reduced numbers of functional (insulin-secreting) beta-cells in pancreatic islets underlies diabetes. Restoration of the secretion of the proper amount of insulin is a goal. Beta-cell mass is increased by neogenesis, proliferation and...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Association of Anatomists
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371177/ https://www.ncbi.nlm.nih.gov/pubmed/25806118 http://dx.doi.org/10.5115/acb.2015.48.1.16 |