Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells

Treatment with cisplatin for cancer therapy has a major side effect such as nephrotoxicity; however, the role of poly (ADP-ribose) polymerase 1 (PARP1) in necrosis in response to cisplatin nephrotoxicity remains to be defined. Here we report that cisplatin induces primary necrosis through PARP1 acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Seulgee, Yoon, Sang Pil, Kim, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371183/
https://www.ncbi.nlm.nih.gov/pubmed/25806124
http://dx.doi.org/10.5115/acb.2015.48.1.66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371183/
https://www.ncbi.nlm.nih.gov/pubmed/25806124
http://dx.doi.org/10.5115/acb.2015.48.1.66

Ejemplares similares