BAY 41-2272 activates host defence against local and disseminated Candida albicans infections

In our previous study, we have found that 5-cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]-pyrimidin-4-ylamine (BAY 41-2272), a guanylate cyclase agonist, activates human monocytes and the THP-1 cell line to produce the superoxide anion, increasing in vitro microbicidal activity...

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Detalles Bibliográficos
Autores principales: Soeiro-Pereira, Paulo Vítor, Falcai, Angela, Kubo, Christina Arslanian, Antunes, Edson, Condino-Neto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371220/
https://www.ncbi.nlm.nih.gov/pubmed/25742266
http://dx.doi.org/10.1590/0074-02760140255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371220/
https://www.ncbi.nlm.nih.gov/pubmed/25742266
http://dx.doi.org/10.1590/0074-02760140255

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