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A new classifier-based strategy for in-silico ion-channel cardiac drug safety assessment
There is currently a strong interest in using high-throughput in-vitro ion-channel screening data to make predictions regarding the cardiac toxicity potential of a new compound in both animal and human studies. A recent FDA think tank encourages the use of biophysical mathematical models of cardiac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371651/ https://www.ncbi.nlm.nih.gov/pubmed/25852560 http://dx.doi.org/10.3389/fphar.2015.00059 |