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Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia

BACKGROUND: Melatonin, a well-known antioxidant, has been shown to possess anti-invasive properties for glioma. However, little is known about the effect of melatonin on glioma cell migration and invasion under hypoxia, which is a crucial microenvironment for tumor progress. In addition, focal adhes...

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Detalles Bibliográficos
Autores principales: Xu, Cheng-Shi, Wang, Ze-Fen, Huang, Xiao-Dong, Dai, Li-Ming, Cao, Chang-Jun, Li, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371719/
https://www.ncbi.nlm.nih.gov/pubmed/25889845
http://dx.doi.org/10.1186/s12967-015-0454-8