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Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia
BACKGROUND: Melatonin, a well-known antioxidant, has been shown to possess anti-invasive properties for glioma. However, little is known about the effect of melatonin on glioma cell migration and invasion under hypoxia, which is a crucial microenvironment for tumor progress. In addition, focal adhes...
Autores principales: | Xu, Cheng-Shi, Wang, Ze-Fen, Huang, Xiao-Dong, Dai, Li-Ming, Cao, Chang-Jun, Li, Zhi-Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371719/ https://www.ncbi.nlm.nih.gov/pubmed/25889845 http://dx.doi.org/10.1186/s12967-015-0454-8 |
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