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Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

Hippocampal network activity is predominantly coordinated by γ-amino-butyric acid (GABA)ergic neurons. We have previously hypothesized that the altered excitability of hippocampal neurons in Alzheimer's disease (AD), which manifests as increased in vivo susceptibility to seizures in the TgCRND8...

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Detalles Bibliográficos
Autores principales: Albuquerque, Marilia S., Mahar, Ian, Davoli, Maria Antonietta, Chabot, Jean-Guy, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371759/
https://www.ncbi.nlm.nih.gov/pubmed/25852545
http://dx.doi.org/10.3389/fnagi.2015.00030