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Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease
Hippocampal network activity is predominantly coordinated by γ-amino-butyric acid (GABA)ergic neurons. We have previously hypothesized that the altered excitability of hippocampal neurons in Alzheimer's disease (AD), which manifests as increased in vivo susceptibility to seizures in the TgCRND8...
Autores principales: | Albuquerque, Marilia S., Mahar, Ian, Davoli, Maria Antonietta, Chabot, Jean-Guy, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371759/ https://www.ncbi.nlm.nih.gov/pubmed/25852545 http://dx.doi.org/10.3389/fnagi.2015.00030 |
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