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Inorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patterns

BACKGROUND: Arsenic (As) exposure is a significant worldwide environmental health concern. Low dose, chronic arsenic exposure has been associated with a higher than normal risk of skin, lung, and bladder cancer, as well as cardiovascular disease and diabetes. While arsenic-induced biological changes...

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Detalles Bibliográficos
Autores principales: Riedmann, Caitlyn, Ma, Ye, Melikishvili, Manana, Godfrey, Steven Grason, Zhang, Zhou, Chen, Kuey Chu, Rouchka, Eric C, Fondufe-Mittendorf, Yvonne N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371809/
https://www.ncbi.nlm.nih.gov/pubmed/25879800
http://dx.doi.org/10.1186/s12864-015-1295-9