Cargando…

Inorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patterns

BACKGROUND: Arsenic (As) exposure is a significant worldwide environmental health concern. Low dose, chronic arsenic exposure has been associated with a higher than normal risk of skin, lung, and bladder cancer, as well as cardiovascular disease and diabetes. While arsenic-induced biological changes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riedmann, Caitlyn, Ma, Ye, Melikishvili, Manana, Godfrey, Steven Grason, Zhang, Zhou, Chen, Kuey Chu, Rouchka, Eric C, Fondufe-Mittendorf, Yvonne N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371809/ https://www.ncbi.nlm.nih.gov/pubmed/25879800 http://dx.doi.org/10.1186/s12864-015-1295-9

Ejemplares similares

Transcriptome-wide identification of the RNA-binding landscape of the chromatin-associated protein PARP1 reveals functions in RNA biogenesis
por: Melikishvili, Manana, et al.
Publicado: (2017)

Genome-wide DNA methylation reprogramming in response to inorganic arsenic links inhibition of CTCF binding, DNMT expression and cellular transformation
por: Rea, Matthew, et al.
Publicado: (2017)

Coupling of PARP1-mediated chromatin structural changes to transcriptional RNA polymerase II elongation and cotranscriptional splicing
por: Matveeva, Elena A., et al.
Publicado: (2019)

Comparative analysis of linker histone H1, MeCP2, and HMGD1 on nucleosome stability and target site accessibility
por: Riedmann, Caitlyn, et al.
Publicado: (2016)

Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition
por: Eckstein, Meredith, et al.
Publicado: (2017)

Microarray dataset of transient and permanent DNA methylation changes in HeLa cells undergoing inorganic arsenic-mediated epithelial-to-mesenchymal transition
por: Eckstein, Meredith, et al.
Publicado: (2017)

Sudemycin E influences alternative splicing and changes chromatin modifications
por: Convertini, Paolo, et al.
Publicado: (2014)

Involvement of PARP1 in the regulation of alternative splicing
por: Matveeva, Elena, et al.
Publicado: (2016)

The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulation
por: Nalabothula, Narasimharao, et al.
Publicado: (2014)

PARP1 Regulates Circular RNA Biogenesis though Control of Transcriptional Dynamics
por: Eleazer, Rebekah, et al.
Publicado: (2023)

Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals
por: Field, Yair, et al.
Publicado: (2008)

The multifaceted role of PARP1 in RNA biogenesis
por: Eleazer, Rebekah, et al.
Publicado: (2020)

Arsenic Methyltransferase and Methylation of Inorganic Arsenic
por: Roy, Nirmal K., et al.
Publicado: (2020)

Lesion-specific DNA-binding and repair activities of human O(6)-alkylguanine DNA alkyltransferase
por: Melikishvili, Manana, et al.
Publicado: (2012)

Resolving the contributions of two cooperative mechanisms to the DNA Binding of AGT
por: Melikishvili, Manana, et al.
Publicado: (2015)

Quaternary interactions and supercoiling modulate the cooperative DNA binding of AGT
por: Melikishvili, Manana, et al.
Publicado: (2017)

PARP1′s Involvement in RNA Polymerase II Elongation: Pausing and Releasing Regulation through the Integrator and Super Elongation Complex
por: Matveeva, Elena A., et al.
Publicado: (2022)

Genome-Wide Profiling of PARP1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation
por: Nalabothula, Narasimharao, et al.
Publicado: (2015)

Biosensors for Inorganic and Organic Arsenicals
por: Chen, Jian, et al.
Publicado: (2014)

Cooperative cluster formation, DNA bending and base-flipping by O(6)-alkylguanine-DNA alkyltransferase
por: Tessmer, Ingrid, et al.
Publicado: (2012)

PARP1 is a versatile factor in the regulation of mRNA stability and decay
por: Matveeva, Elena A., et al.
Publicado: (2019)

Evaluation of Plasma Arsenicals as Potential Biomarkers of Exposure to Inorganic Arsenic
por: Bommarito, Paige A., et al.
Publicado: (2019)

Inorganic Arsenic and Human Prostate Cancer
por: Benbrahim-Tallaa, Lamia, et al.
Publicado: (2008)

Chronic dietary exposure to inorganic arsenic
por: Arcella, Davide, et al.
Publicado: (2021)

A biological indicator of inorganic arsenic exposure using the sum of urinary inorganic arsenic and monomethylarsonic acid concentrations
por: Hata, Akihisa, et al.
Publicado: (2016)

Accumulation and transformation of inorganic and organic arsenic in rice and role of thiol-complexation to restrict their translocation to shoot
por: Mishra, Seema, et al.
Publicado: (2017)

Arsenical Association: Inorganic Arsenic May Accumulate in the Meat of Treated Chickens
por: Schmidt, Charles W.
Publicado: (2013)

Significant Biotransformation of Arsenobetaine into Inorganic Arsenic in Mice
por: Zhang, Jichao, et al.
Publicado: (2023)

Metabolism of inorganic arsenic in children with chronic high arsenic exposure in northern Argentina.
por: Concha, G, et al.
Publicado: (1998)

Erratum: “Arsenical Association: Inorganic Arsenic May Accumulate in the Meat of Treated Chickens”
Publicado: (2013)

Urinary Trivalent Methylated Arsenic Species in a Population Chronically Exposed to Inorganic Arsenic
por: Valenzuela, Olga L., et al.
Publicado: (2005)

Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element
por: Lu, Peng, et al.
Publicado: (2008)

Predicting nucleosome positioning using a duration Hidden Markov Model
por: Xi, Liqun, et al.
Publicado: (2010)

Biomarkers of Exposure: A Case Study with Inorganic Arsenic
por: Hughes, Michael F.
Publicado: (2006)

Organic versus Inorganic Arsenic in Herbal Kelp Supplements
por: Lewis, Ari S.
Publicado: (2007)

Freshwater phytoplankton: biotransformation of inorganic arsenic to methylarsenic and organoarsenic
por: Hasegawa, Hiroshi, et al.
Publicado: (2019)

Inter‐ and Transgenerational Effects of Paternal Exposure to Inorganic Arsenic
por: Gong, Yingyun, et al.
Publicado: (2021)

Preferentially Quantized Linker DNA Lengths in Saccharomyces cerevisiae
por: Wang, Ji-Ping, et al.
Publicado: (2008)

Inorganic arsenic: a need and an opportunity to improve risk assessment.
por: Chappell, W R, et al.
Publicado: (1997)

Impact of Water Regimes and Amendments on Inorganic Arsenic Exposure to Rice
por: Majumder, Supriya, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_db2lj545nsf80k2hsvl6halnmj