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Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells

BACKGROUND: Diabetes mellitus is a common metabolic disorder characterized by dysfunction of insulin-secreting pancreatic beta-cells. MicroRNAs are important regulators of beta-cell activities. These non-coding RNAs have recently been discovered to exert their effects not only inside the cell produc...

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Detalles Bibliográficos
Autores principales: Guay, Claudiane, Menoud, Véronique, Rome, Sophie, Regazzi, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371845/
https://www.ncbi.nlm.nih.gov/pubmed/25880779
http://dx.doi.org/10.1186/s12964-015-0097-7