Broad Blockade Antibody Responses in Human Volunteers after Immunization with a Multivalent Norovirus VLP Candidate Vaccine: Immunological Analyses from a Phase I Clinical Trial

BACKGROUND: Human noroviruses (NoVs) are the primary cause of acute gastroenteritis and are characterized by antigenic variation between genogroups and genotypes and antigenic drift of strains within the predominant GII.4 genotype. In the context of this diversity, an effective NoV vaccine must elic...

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Detalles Bibliográficos
Autores principales: Lindesmith, Lisa C., Ferris, Martin T., Mullan, Clancy W., Ferreira, Jennifer, Debbink, Kari, Swanstrom, Jesica, Richardson, Charles, Goodwin, Robert R., Baehner, Frank, Mendelman, Paul M., Bargatze, Robert F., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371888/
https://www.ncbi.nlm.nih.gov/pubmed/25803642
http://dx.doi.org/10.1371/journal.pmed.1001807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371888/
https://www.ncbi.nlm.nih.gov/pubmed/25803642
http://dx.doi.org/10.1371/journal.pmed.1001807

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