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The antitumor activity of tumor-homing peptide-modified thermosensitive liposomes containing doxorubicin on MCF-7/ADR: in vitro and in vivo

Clotted plasma proteins are present on the walls of tumor vessels and in tumor stroma. Tumor-homing peptide Cys-Arg-Glu-Lys-Ala (CREKA) could recognize the clotted plasma proteins in tumor vessels. Thermosensitive liposomes could immediately release the encapsulated drug in the vasculature of the he...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Wang, Xin, Zhong, Ting, Zhao, Yang, Zhang, Wei-Qiang, Ren, Wei, Huang, Dan, Zhang, Shuang, Guo, Yang, Yao, Xin, Tang, Yi-Qun, Zhang, Xuan, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372005/
https://www.ncbi.nlm.nih.gov/pubmed/25834435
http://dx.doi.org/10.2147/IJN.S79840