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Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo
Mutations are a critical driver of cancer initiation. While extensive studies have focused on exposure-induced mutations, few studies have explored the importance of tissue physiology as a modulator of mutation susceptibility in vivo. Of particular interest is inflammation, a known cancer risk facto...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372043/ https://www.ncbi.nlm.nih.gov/pubmed/25647331 http://dx.doi.org/10.1371/journal.pgen.1004901 |