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CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women

INTRODUCTION: Rheumatoid arthritis (RA) is characterized by decreased androgen levels, which was the first hormonal abnormality described. Several studies indicated that steroidogenesis is directed towards endogenous glucocorticoids at the expense of androgens. The decisive step governing androgen s...

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Detalles Bibliográficos
Autores principales: Stark, Klaus, Straub, Rainer H, Rovenský, Jozef, Blažičková, Stanislava, Eiselt, Gabriele, Schmidt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372052/
https://www.ncbi.nlm.nih.gov/pubmed/25890314
http://dx.doi.org/10.1186/s13075-015-0574-9