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Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains

[Image: see text] Protein ubiquitylation, one of the most prevalent post-translational modifications in eukaryotes, is involved in regulating nearly every cellular signaling pathway. The vast functional range of ubiquitylation has largely been attributed to the formation of a diverse array of polyme...

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Detalles Bibliográficos
Autores principales: Valkevich, Ellen M., Sanchez, Nicholas A., Ge, Ying, Strieter, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372068/
https://www.ncbi.nlm.nih.gov/pubmed/25023374
http://dx.doi.org/10.1021/bi5006305