Cargando…

Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer

Mutations in the KRAS oncogene represent one of the most prevalent genetic alterations in colorectal cancer (CRC), the third leading cause of cancer-related death in the US. In addition to their well-characterized function in driving tumor progression, KRAS mutations have been recognized as a critic...

Descripción completa

Detalles Bibliográficos
Autores principales: Knickelbein, Kyle, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372129/
https://www.ncbi.nlm.nih.gov/pubmed/25815366
http://dx.doi.org/10.1016/j.gendis.2014.10.002