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Genomic Characterization of Burkholderia pseudomallei Isolates Selected for Medical Countermeasures Testing: Comparative Genomics Associated with Differential Virulence

Burkholderia pseudomallei is the causative agent of melioidosis and a potential bioterrorism agent. In the development of medical countermeasures against B. pseudomallei infection, the US Food and Drug Administration (FDA) animal Rule recommends using well-characterized strains in animal challenge s...

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Detalles Bibliográficos
Autores principales: Sahl, Jason W., Allender, Christopher J., Colman, Rebecca E., Califf, Katy J., Schupp, James M., Currie, Bart J., Van Zandt, Kristopher E., Gelhaus, H. Carl, Keim, Paul, Tuanyok, Apichai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372212/
https://www.ncbi.nlm.nih.gov/pubmed/25803742
http://dx.doi.org/10.1371/journal.pone.0121052