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Genomic Characterization of Burkholderia pseudomallei Isolates Selected for Medical Countermeasures Testing: Comparative Genomics Associated with Differential Virulence
Burkholderia pseudomallei is the causative agent of melioidosis and a potential bioterrorism agent. In the development of medical countermeasures against B. pseudomallei infection, the US Food and Drug Administration (FDA) animal Rule recommends using well-characterized strains in animal challenge s...
Autores principales: | Sahl, Jason W., Allender, Christopher J., Colman, Rebecca E., Califf, Katy J., Schupp, James M., Currie, Bart J., Van Zandt, Kristopher E., Gelhaus, H. Carl, Keim, Paul, Tuanyok, Apichai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372212/ https://www.ncbi.nlm.nih.gov/pubmed/25803742 http://dx.doi.org/10.1371/journal.pone.0121052 |
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