QSAR based model for discriminating EGFR inhibitors and non-inhibitors using Random forest

BACKGROUND: Epidermal Growth Factor Receptor (EGFR) is a well-characterized cancer drug target. In the past, several QSAR models have been developed for predicting inhibition activity of molecules against EGFR. These models are useful to a limited set of molecules for a particular class like quinazo...

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Detalles Bibliográficos
Autores principales: Singh, Harinder, Singh, Sandeep, Singla, Deepak, Agarwal, Subhash M, Raghava, Gajendra P S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372225/
https://www.ncbi.nlm.nih.gov/pubmed/25880749
http://dx.doi.org/10.1186/s13062-015-0046-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372225/
https://www.ncbi.nlm.nih.gov/pubmed/25880749
http://dx.doi.org/10.1186/s13062-015-0046-9

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