Cargando…
QSAR based model for discriminating EGFR inhibitors and non-inhibitors using Random forest
BACKGROUND: Epidermal Growth Factor Receptor (EGFR) is a well-characterized cancer drug target. In the past, several QSAR models have been developed for predicting inhibition activity of molecules against EGFR. These models are useful to a limited set of molecules for a particular class like quinazo...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372225/ https://www.ncbi.nlm.nih.gov/pubmed/25880749 http://dx.doi.org/10.1186/s13062-015-0046-9 |