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Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch

The gate control theory of pain proposes that inhibitory neurons of the spinal dorsal horn exert critical control over the relay of nociceptive signals to higher brain areas. Here we investigated how the glycinergic subpopulation of these neurons contributes to modality-specific pain and itch proces...

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Detalles Bibliográficos
Autores principales: Foster, Edmund, Wildner, Hendrik, Tudeau, Laetitia, Haueter, Sabine, Ralvenius, William T., Jegen, Monika, Johannssen, Helge, Hösli, Ladina, Haenraets, Karen, Ghanem, Alexander, Conzelmann, Karl-Klaus, Bösl, Michael, Zeilhofer, Hanns Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372258/
https://www.ncbi.nlm.nih.gov/pubmed/25789756
http://dx.doi.org/10.1016/j.neuron.2015.02.028