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Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A

BACKGROUND: Granulocyte colony-stimulating factor (G-CSF) promotes proliferation, survival, and differentiation of myeloid-linage leukemic cells, as well as normal hematopoietic cells. Terminal granulocytic differentiation can be induced in acute promyelocytic (APL) cell line HT93A by G-CSF and all-...

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Detalles Bibliográficos
Autores principales: Uchino, Yoshihito, Iriyama, Noriyoshi, Hatta, Yoshihiro, Takei, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372317/
https://www.ncbi.nlm.nih.gov/pubmed/25805962
http://dx.doi.org/10.1186/s12935-015-0176-2