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Variant rs1801157 in the 3’UTR of SDF-1ß Does Not Explain Variability of Healthy-Donor G-CSF Responsiveness

The genetics responsible for the inter-individually variable G-CSF responsiveness remain elusive. A single nucleotide polymorphism (SNP) in the 3’UTR of CXCL12, rs1801157, was implicated in X4-tropic HiV susceptibility and later, in two small studies, in G-CSR responsiveness in patients and donors....

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Detalles Bibliográficos
Autores principales: Schulz, Miriam, Karpova, Darja, Spohn, Gabriele, Damert, Annette, Seifried, Erhard, Binder, Vera, Bönig, Halvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372333/
https://www.ncbi.nlm.nih.gov/pubmed/25803672
http://dx.doi.org/10.1371/journal.pone.0121859