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Assessment of In Vivo and In Vitro Genotoxicity of Glibenclamide in Eukaryotic Cells

Glibenclamide is an oral hypoglycemic drug commonly prescribed for the treatment of type 2 diabetes mellitus, whose anti-tumor activity has been recently described in several human cancer cells. The mutagenic potential of such an antidiabetic drug and its recombinogenic activity in eukaryotic cells...

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Detalles Bibliográficos
Autores principales: de Sant’Anna, Juliane Rocha, Franco, Claudinéia Conationi da Silva, Mathias, Paulo Cezar de Freitas, de Castro-Prado, Marialba Avezum Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372363/
https://www.ncbi.nlm.nih.gov/pubmed/25803314
http://dx.doi.org/10.1371/journal.pone.0120675