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Assessment of In Vivo and In Vitro Genotoxicity of Glibenclamide in Eukaryotic Cells
Glibenclamide is an oral hypoglycemic drug commonly prescribed for the treatment of type 2 diabetes mellitus, whose anti-tumor activity has been recently described in several human cancer cells. The mutagenic potential of such an antidiabetic drug and its recombinogenic activity in eukaryotic cells...
Autores principales: | de Sant’Anna, Juliane Rocha, Franco, Claudinéia Conationi da Silva, Mathias, Paulo Cezar de Freitas, de Castro-Prado, Marialba Avezum Alves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372363/ https://www.ncbi.nlm.nih.gov/pubmed/25803314 http://dx.doi.org/10.1371/journal.pone.0120675 |
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