Potentiation of Epidermal Growth Factor-Mediated Oncogenic Transformation by Sialidase NEU3 Leading to Src Activation

We previously demonstrated that sialidase NEU3, a key glycosidase for ganglioside degradation, is up-regulated in various human cancers, leading to increased cell invasion, motility and survival of cancer cells possibly through activation of EGF signaling. Its up-regulation is also important for pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Koji, Takahashi, Kohta, Shiozaki, Kazuhiro, Yamaguchi, Kazunori, Moriya, Setsuko, Hosono, Masahiro, Shima, Hiroshi, Miyagi, Taeko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372364/
https://www.ncbi.nlm.nih.gov/pubmed/25803810
http://dx.doi.org/10.1371/journal.pone.0120578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372364/
https://www.ncbi.nlm.nih.gov/pubmed/25803810
http://dx.doi.org/10.1371/journal.pone.0120578

Ejemplares similares