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Cytotoxic Helix-Rich Oligomer Formation by Melittin and Pancreatic Polypeptide
Conversion of amyloid fibrils by many peptides/proteins involves cytotoxic helix-rich oligomers. However, their toxicity and biophysical studies remain largely unknown due to their highly dynamic nature. To address this, we chose two helical peptides (melittin, Mel and pancreatic polypeptide, PP) an...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372375/ https://www.ncbi.nlm.nih.gov/pubmed/25803428 http://dx.doi.org/10.1371/journal.pone.0120346 |