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Cytotoxic Helix-Rich Oligomer Formation by Melittin and Pancreatic Polypeptide

Conversion of amyloid fibrils by many peptides/proteins involves cytotoxic helix-rich oligomers. However, their toxicity and biophysical studies remain largely unknown due to their highly dynamic nature. To address this, we chose two helical peptides (melittin, Mel and pancreatic polypeptide, PP) an...

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Detalles Bibliográficos
Autores principales: Singh, Pradeep K., Ghosh, Dhiman, Tewari, Debanjan, Mohite, Ganesh M., Carvalho, Edmund, Jha, Narendra Nath, Jacob, Reeba S., Sahay, Shruti, Banerjee, Rinti, Bera, Amal K., Maji, Samir K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372375/
https://www.ncbi.nlm.nih.gov/pubmed/25803428
http://dx.doi.org/10.1371/journal.pone.0120346